Filling of wrinkles and lines 

For this purpose, biocompatible materials can be injected, as Perlane, Restilane, and Restilane for fine lines. The body degrades all these products, so they are not permanent and last for about 6 to 7 month. They are basically used for the filling of lines which run from the nose to the mouth, and lines that are over the upper lip. No serious secondary reactions have been registered. 

Another alternative of filling is the use of the own patientís fat in the nasal

creases, (Lines that run from the nose to the mouth).